Anti-SIN3A Antibody

Antibodies.com provides this rabbit polyclonal reagent raised against the SIN3A transcriptional corepressor, shipped as a 100 µL vial of unconjugated antiserum. SIN3A functions as a scaffold protein within the Sin3A–HDAC complex, recruiting histone deacetylases to chromatin and repressing transcription of target genes involved in cell cycle control and differentiation.

The antibody has been validated across Western blot, immunoprecipitation, and chromatin immunoprecipitation workflows, and is additionally suited to immunohistochemistry and immunofluorescence for mapping SIN3A distribution in fixed tissues and cultured cells. Reactivity is documented against human, mouse, and rat samples, making it broadly applicable across common model systems.

Because the reagent is supplied unconjugated, it can be paired with HRP, fluorophore, or biotin labeling chemistries according to the experimental design. The polyclonal format offers recognition of multiple epitopes on SIN3A, useful for capturing the full-length protein and probing isoforms in chromatin remodeling studies.