Anti-SIGLEC6 Antibody

The Antibodies.com polyclonal reagent targets SIGLEC6, a sialic acid-binding immunoglobulin-like lectin expressed on placental trophoblasts, B lymphocytes, and mast cells. Raised in rabbit, this unconjugated IgG antibody recognizes both human and mouse SIGLEC6, supporting cross-species comparative studies in placental biology, gestational immunology, and innate immune signaling research.

Validated for Western blot (WB) and immunohistochemistry (IHC), the antibody enables detection of endogenous SIGLEC6 protein in tissue sections and whole-cell lysates. Each vial is supplied as 200 µL of liquid format, ready for dilution into standard immunostaining or blotting workflows. The unconjugated chemistry allows pairing with secondary reagents for fluorescence, chromogenic, or chemiluminescent readouts.

SIGLEC6 expression is associated with trophoblast function and a subset of circulating B cells, making this reagent useful in studies on pregnancy-related immune tolerance, decidual biology, and CD22-family lectin behavior. Store refrigerated; protect from light and avoid repeated freeze-thaw cycles to preserve antibody activity. For research use only.