Anti-SIGLEC12 Antibody

SIGLEC12 is a member of the sialic acid-binding immunoglobulin-like lectin family, with expression reported on immune cells and on several cancer types including prostate carcinoma. This unconjugated rabbit polyclonal reagent from Antibodies.com targets SIGLEC12 for use in Western blot and immunohistochemistry workflows, with reactivity validated against human and mouse samples. Supplied as 100 µl of polyclonal antiserum raised in rabbit, the antibody supports detection of endogenous SIGLEC12 in tissue sections and immunoblot membranes without the need for a secondary conjugation step. Researchers studying siglec biology, tumor-associated glycobiology, or innate immune signaling can apply the reagent to formalin-fixed paraffin-embedded sections for IHC and to standard SDS-PAGE lysates for WB. The polyclonal format increases the likelihood of recognizing multiple epitopes across the SIGLEC12 extracellular and cytoplasmic regions, which is useful when probing low-abundance targets or when working with samples where post-translational glycosylation may mask individual epitopes.