Anti-SHMT2 Antibody

This rabbit polyclonal antibody from Antibodies.com binds SHMT2, the mitochondrial serine hydroxymethyltransferase that converts serine to glycine and supports one-carbon folate metabolism in proliferating cells. Delivered unconjugated in a 100 µl vial, the reagent is validated for Western blot, immunohistochemistry, and immunofluorescence work on human, mouse, and rat specimens, enabling comparative studies of mitochondrial enzyme expression in cancer metabolism research and tissue-based investigations. Investigators routinely apply the antibody to characterize SHMT2 levels across transformed versus normal cell lines and to localize the protein in fixed tissue sections. Aliquot upon receipt, refrigerate for short-term use, and minimize freeze-thaw cycles to preserve binding activity over the working shelf life.