Anti-SH3GLB1 Antibody

SH3GLB1, also known as Bif-1 and Endophilin B1, is a multifunctional adaptor protein whose BAR domain senses and shapes mitochondrial membranes while its SH3 domain recruits Beclin-1 to drive autophagy and apoptosis signaling. This rabbit polyclonal IgG reagent from Antibodies.com detects the human SH3GLB1 isoform in Western blot workflows and immunohistochemistry on formalin-fixed paraffin-embedded sections. The unconjugated antibody is supplied as 100 µl of stock; storage at -20 °C in small aliquots is recommended to limit freeze-thaw exposure and preserve binding titer across many experiments. Investigators studying mitophagy, Parkin-mediated mitochondrial turnover, Bax-driven outer membrane permeabilization, or SH3GLB1 loss in carcinoma models use this reagent to map Bif-1 expression across cell lines and clinical biopsy material.