Anti-SH2D1A Antibody

This polyclonal antibody from Antibodies.com targets SH2D1A, also known as SAP (SLAM-associated protein), a small adaptor protein essential for SLAM family receptor signaling in lymphocytes. Raised in rabbit hosts and unconjugated, it is validated for Western blot detection of endogenous SAP in human and mouse samples. Each vial contains 200 µl of polyclonal IgG for probing immune cell lysates, lymph node tissue, and transfected cell lines expressing SH2D1A. The reagent is commonly deployed in studies of X-linked lymphoproliferative disease (XLP-1), EBV-driven immune dysregulation, NK cell activation, T cell-B cell conjugation, and thymic selection. Researchers investigating SLAM/SAP pathway components in autoimmune or immunodeficiency models use this antibody to track protein expression changes following genetic perturbation or viral challenge. Store refrigerated; aliquot to avoid repeated freeze-thaw cycles and protect from light for long-term stability.