Anti-SH-PTP2 Antibody

SHP-2 (also called SH-PTP2) is a non-receptor protein tyrosine phosphatase encoded by the PTPN11 gene that operates downstream of growth factor, cytokine, and integrin receptors. This Rabbit polyclonal primary antibody from Antibodies.com is raised against SH-PTP2 and validated for Western blot and immunohistochemistry workflows. The unconjugated reagent is supplied as 100 µl of polyclonal antiserum and detects endogenous SH-PTP2 in Human, Mouse, and Rat samples, supporting cross-species studies of RAS/MAPK, PI3K, and JAK/STAT signaling. Researchers apply this reagent to probe phosphatase expression in Noonan syndrome and LEOPARD syndrome models, examine juvenile myelomonocytic leukemia cell lines, and profile developmental signaling cascades, where reliable recognition of full-length SHP-2 (approximately 72 kDa) by Western blot is critical.