Anti-SH-PTP2 Antibody

A cytoplasmic non-receptor tyrosine phosphatase built around two Src homology 2 (SH2) domains, SH-PTP2 (also known as SHP-2, PTP-1D, or PTPN11) modulates RAS-MAPK signaling downstream of growth factor, cytokine, and integrin receptors, and germline mutations in the PTPN11 gene are linked to Noonan syndrome and LEOPARD syndrome. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against SH-PTP2 and validated for western blot, immunohistochemistry, and ELISA workflows on human, mouse, and rat samples, supplied as 100 µl of polyclonal antiserum for in vitro research use only.