Anti-SH-PTP2 Antibody

SHP-2 (Src homology-2 domain-containing protein tyrosine phosphatase 2) is a non-receptor tyrosine phosphatase encoded by the PTPN11 gene that modulates RAS/MAPK and PI3K signaling downstream of receptor tyrosine kinases. The polyclonal reagent from Antibodies.com is raised in rabbit hosts against SH-PTP2 and is supplied as a 100 µl vial of unconjugated antiserum, ready for Western blot, immunohistochemistry, and ELISA workflows. Confirmed reactivity spans human, mouse, and rat samples, supporting translational and comparative studies in common laboratory models. Investigators working on Noonan syndrome, LEOPARD syndrome, and PTPN11-driven oncogenic signaling rely on this reagent to assess expression in cell lysates and fixed tissue sections. The unconjugated format permits downstream conjugation to fluorophores, biotin, or horseradish peroxidase, enabling flexible chromogenic, fluorescent, or amplified readouts depending on the experimental platform.