Anti-SGK1 Antibody

This rabbit polyclonal reagent from Antibodies.com is raised against Serum/Glucocorticoid-Regulated Kinase 1 (SGK1), an AGC-family serine/threonine kinase that responds to glucocorticoids, mineralocorticoids, and cellular stress to modulate ENaC-mediated sodium transport, ion channel activity, and downstream survival signaling through PI3K and mTOR pathways.

The unconjugated antibody is supplied as 100 µl of polyclonal antiserum and is validated for Western blot, immunohistochemistry, and ELISA workflows on human, mouse, and rat samples. Investigators studying renal sodium handling, glucocorticoid-driven hypertension, insulin signaling, or SGK1-dependent tumor progression can use it to probe endogenous kinase levels across cell lines, primary tissue, and archived sections, with the unconjugated format enabling flexible pairing with custom secondary conjugates for chromogenic, fluorescent, or HRP-based detection. For short-term use, aliquot and store refrigerated; avoid repeated freeze-thaw cycles to preserve reagent performance.