Anti-SGCG Antibody

Gamma-sarcoglycan is a transmembrane component of the dystrophin-associated glycoprotein complex that anchors the sarcolemma in skeletal and cardiac muscle. The polyclonal SGCG antibody from Antibodies.com is raised in rabbit and supplied as an unconjugated IgG preparation at 50 µl, validated for Western blot detection of the human γ-sarcoglycan protein.

Investigators working on limb-girdle muscular dystrophy type 2C (LGMD2C), severe childhood autosomal recessive muscular dystrophy (SCARMD), and related sarcoglycanopathies rely on this reagent to characterize γ-sarcoglycan expression in patient-derived skeletal muscle biopsies, primary myoblast cultures, and dystrophinopathy model systems. Reactivity with the human target supports translational studies, while the polyclonal format provides recognition of multiple epitopes across the protein.

For best long-term stability, aliquot the antibody vial upon first thaw and store the working stock at -20°C, avoiding repeated freeze-thaw cycles; briefly refrigerated storage at 4°C is appropriate for active aliquots used within a few days. For research use only.