Anti-SFTPC Antibody

The Antibodies.com rabbit polyclonal reagent targets Surfactant Protein C (SFTPC), a hydrophobic peptide secreted by alveolar type II pneumocytes and essential for reducing surface tension at the air-liquid interface of the lung. Investigators working on pulmonary surfactant biology, neonatal respiratory distress syndrome, and interstitial lung disease use this unconjugated primary antibody in Western blot, immunohistochemistry, and immunofluorescence workflows on human tissue samples. The reagent is supplied as 100 µl of polyclonal antiserum raised in rabbit, suitable for detection of the full-length proprotein and processed mature forms in lung-derived cell lysates and paraffin-embedded sections. Specificity has been validated for human SFTPC, a gene whose mutations are associated with both sporadic and familial interstitial lung disease. Researchers studying idiopathic pulmonary fibrosis, surfactant metabolism dysfunction, and alveolar epithelial differentiation rely on SFTPC as a type II cell marker, and this reagent supports co-localization studies with transcription factors such as NKX2-1 in airway epithelium models.