Anti-SFTPB Antibody

Raised in rabbit against pulmonary Surfactant Protein B, this polyclonal antibody from Antibodies.com is validated for Western Blot detection of SFTPB across human, mouse, and rat samples. SFTPB is a hydrophobic lipoprotein essential for lowering alveolar surface tension and stabilizing the air-liquid interface in mammalian lungs, where it is transcribed primarily in bronchiolar and alveolar type II epithelial cells and supports biophysical surfactant activity at the phospholipid film.

The unconjugated IgG reagent is supplied as 100 µl of stock solution suitable for standard immunoblotting workflows using whole-cell or tissue lysates from lung homogenates. The antibody can be used to evaluate precursor proprotein processing and the small hydrophobic mature peptide forms in conditioned media or tissue extracts, supporting research into neonatal respiratory distress syndrome, hereditary surfactant deficiency, COPD, acute lung injury, and pulmonary fibrotic remodeling. Refrigerate upon arrival and protect from repeated freeze-thaw cycles to preserve binding activity across multiple experiments.