Anti-SFRP4 Antibody

This polyclonal antibody from Antibodies.com targets SFRP4 (Secreted Frizzled-Related Protein 4), a soluble modulator of the Wnt/β-catenin signaling pathway implicated in tumor suppression, apoptosis regulation, and metabolic homeostasis. Produced in rabbit and supplied as an unconjugated reagent in 100 µl, the antibody supports Western blot and immunofluorescence workflows across human, mouse, and rat samples.

SFRP4 expression has been documented in tissues including kidney, endometrium, ovary, and several epithelial cancers, where it is studied as a candidate biomarker for diabetic kidney disease progression and for tumor-associated methylation changes. Researchers investigating Wnt pathway dysregulation, adipocyte differentiation, or epithelial-to-mesenchymal transition use this reagent to detect the endogenous protein in cell lysates and fixed sections.

The polyclonal format offers multi-epitope recognition, which is helpful for tracking processed forms and post-translational modifications of the target. Aliquot on arrival and store refrigerated; avoid repeated freeze-thaw cycles to preserve activity across multiple experiments.