Anti-SFRP2 Antibody

Raised in rabbit against Secreted Frizzled Related Protein 2, this polyclonal reagent from Antibodies.com targets an extracellular modulator of Wnt signaling that binds Wnt ligands through a cysteine-rich domain homologous to the Frizzled receptor. The unconjugated antibody is supplied as 100 µl of antiserum in a vial and is validated for Western blot and immunofluorescence applications across human, mouse, and rat samples.

SFRP2 expression is studied in colorectal, breast, and gastric cancer biology, as well as in models of cardiac fibrosis, osteoblast differentiation, and bone formation. Researchers use this reagent to probe how Wnt pathway inhibition shapes the tumor microenvironment and how SFRP2 contributes to developmental signaling. On Western blot, the expected band migrates near the predicted molecular weight of approximately 33 kDa.

For best results, aliquot upon arrival, store refrigerated, and minimize freeze-thaw cycles. The product is intended for research use only and is not for diagnostic or therapeutic applications.