Anti-SETDB1 Antibody

Manufactured by Antibodies.com, this affinity-purified polyclonal reagent is raised in rabbit against recombinant human SETDB1 (also known as ESET, KG1T, KIAA0067, KMT1E, or TDRD21), enabling selective detection of endogenous total SETDB1 protein across human, mouse, and rat samples. The unconjugated IgG antibody is supplied at a concentration of 1.0 mg/mL in a 50 µL volume, formulated in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol. It is validated for Western blotting (WB) and immunocytochemistry/immunofluorescence (ICC/IF), making it suitable for chromatin-associated and nuclear localisation studies. The immunogen is a recombinant fragment of human SETDB1, and the antibody is purified by affinity chromatography against the immunogen to minimise non-specific binding. Shipping is performed at 4 °C; upon receipt, aliquots should be stored at –20 °C with freeze/thaw cycles kept to a minimum to preserve reactivity. For research use only, the reagent is intended to support investigations into histone methylation, transcriptional repression, and related epigenetic mechanisms in cell and tissue lysates.