Anti-SERPINH1 Antibody

This unconjugated rabbit IgG primary antibody recognizes human SERPINH1, also known as HSP47, an endoplasmic-reticulum chaperone involved in procollagen folding and secretion. Its biological role makes it relevant to Western blot and immunofluorescence studies of collagen biosynthesis, extracellular-matrix remodeling, and fibrotic disease models, particularly when examining endogenous protein abundance or intracellular localization.

Supplied in a 100 µl volume, the polyclonal antibody provides human reactivity while allowing researchers to select an appropriate labeled secondary antibody for their detection system. Western blot workflows can use the reagent to evaluate SERPINH1 expression in prepared cell or tissue lysates. Immunofluorescence workflows can assess ER-associated staining in fixed and permeabilized cell samples. Sample preparation, antibody dilution, permeabilization conditions, and imaging settings should be optimized for the chosen specimen and secondary reagent.

Antibodies.com identifies this SERPINH1 antibody as an unconjugated rabbit polyclonal IgG validated for WB and IF applications. It supports laboratory research into collagen-producing cells, matrix biology, and the cellular mechanisms associated with fibrotic change.