Anti-SERPINB9 Antibody

This rabbit polyclonal antibody from Antibodies.com targets SERPINB9 (also called PI9, CAP-3, or cytoplasmic antiproteinase 3), a 42 kDa serine protease inhibitor that uniquely blocks granzyme B-mediated apoptosis and is therefore central to studies of cytotoxic T lymphocyte and NK cell function, immune privilege, and tumor immune evasion.

Validated for western blot and immunohistochemistry on human samples, the unconjugated reagent is supplied as a 100 ul volume of polyclonal antiserum raised in rabbit, helping investigators probe SERPINB9 expression in cytotoxic lymphocytes, placenta, testis, and neoplastic tissues where elevated PI9 levels have been linked to resistance against granzyme B-mediated killing.