Anti-SERPINB1 Antibody

Polyclonal antibodies targeting SERPINB1 (monocyte/neutrophil elastase inhibitor, MNEI) provide a versatile tool for researchers studying innate immunity, neutrophil proteolysis, and inflammatory signaling. Produced in rabbit and supplied at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% glycerol, this unconjugated reagent supports western blot, immunohistochemistry, and immunofluorescence workflows against human, mouse, and rat samples. The 100 µl vial is intended for laboratory research use only and should be stored refrigerated in small aliquots to limit freeze-thaw cycles. SERPINB1 is a clade B serpin that restrains neutrophil elastase, cathepsin G, and proteinase-3, and it has been implicated in COPD, cystic fibrosis, acute lung injury, and keratinocyte differentiation. Confirmed reactivity across human, mouse, and rat samples makes this Antibodies.com reagent well suited for studies of neutrophil extracellular trap regulation, mucosal barrier defense, and protease-antiprotease balance.