Anti-SERPINA6 Antibody

Antibodies.com offers this rabbit polyclonal reagent raised against SERPINA6, the gene that encodes corticosteroid-binding globulin (CBG), a liver-derived serpin responsible for shuttling cortisol and progesterone through the bloodstream and modulating their bioavailability at peripheral target tissues. Supplied as 100 µl of unconjugated antiserum, the antibody is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples, supporting studies of hepatic serpin expression, glucocorticoid transport physiology, and conditions in which circulating CBG levels shift, such as pregnancy, oral contraceptive use, sepsis, and chronic inflammatory disease. The polyclonal format increases the chance of recognizing multiple epitopes on the mature ~50 kDa glycoprotein, which is useful when probing tissue sections in which post-translational glycosylation can mask individual binding sites. Aliquot upon receipt to limit freeze-thaw cycles, store refrigerated at 4 °C for short-term use, and keep at -20 °C for longer-term storage. Each vial contains the antibody in a buffer suitable for direct dilution into standard immunostaining or immunoblotting protocols, and the unconjugated preparation can be paired with secondary reporters chosen for the detection platform in use.