Anti-SERPINA5 Antibody

This rabbit-derived polyclonal reagent from Antibodies.com targets SERPINA5 (Protein C Inhibitor), a serpin family member that regulates serine proteases involved in coagulation, fibrinolysis, and reproductive biology. Raised in rabbit and purified as an IgG preparation, the unconjugated antibody is supplied as a 50 µl aliquot suitable for Western blot and immunohistochemistry workflows on human samples.

SERPINA5 functions as a critical checkpoint against aberrant thrombin, urokinase, and tissue plasminogen activator activity, and altered expression has been documented in liver, kidney, and placental tissues under pathological conditions. Researchers investigating thrombotic disorders, tumor invasion, or reproductive biology use this reagent to probe endogenous protein levels across cell lines and primary tissue sections.

For Western blot, the antibody is generally compatible with standard chemiluminescent detection workflows using HRP-conjugated secondary antibodies; for IHC, it works on formalin-fixed, paraffin-embedded sections following antigen retrieval. Store the vial refrigerated; for longer-term storage, aliquot and freeze at -20 °C to preserve activity. Avoid repeated freeze-thaw cycles.

The unconjugated format offers flexibility: pair it with HRP, fluorescent, or biotin-labeled secondary reagents to match the detection platform of your assay. Each lot is validated for specificity to the SERPINA5 target in human specimens.