Anti-SERPINA1 Antibody

Alpha-1 antitrypsin, encoded by SERPINA1, is a serine protease inhibitor best known for neutralizing neutrophil elastase in the lower respiratory tract. This rabbit polyclonal reagent from Antibodies.com is raised against the human SERPINA1 protein and supplied as an unconjugated 100 µl aliquot for western blot and immunohistochemistry workflows. Human reactivity validation makes the antibody a practical tool for studying alpha-1 antitrypsin deficiency, hepatic Z-allele aggregation, and serpin family biology in cell lysates and fixed tissue sections. The polyclonal format offers multi-epitope recognition, useful when probing denatured SERPINA1 on membranes or formalin-fixed paraffin-embedded material where antigen accessibility can vary. Working stocks can be stored at 4°C for short-term use, while longer-term storage at -20°C in cryoprotectant buffer preserves activity; limit freeze-thaw cycles by aliquoting on first thaw.