Anti-SERP1 Antibody

Antibodies.com supplies this rabbit polyclonal reagent raised against SERP1, a small endoplasmic reticulum membrane protein also known as RAMP4 that participates in the unfolded protein response and helps stabilize nascent polypeptides entering the ER lumen. The unconjugated antibody is provided at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, and the 100 µl vial is intended for Western Blot detection of the target in human, mouse, and rat samples.

SERP1 expression rises during ER stress and has been linked to pancreatic beta-cell survival in knockout mouse studies, making this reagent useful for diabetes, secretory pathway, and cell signalling research. Investigators working on PERK, IRE1, or ATF6 pathways can probe SERP1/RAMP4 levels in lysates from cultured mammalian cells or tissue homogenates. The polyclonal format offers multiple epitope recognition, helpful when detecting the low-abundance endogenous protein on a Western blot membrane.

Aliquot upon arrival and refrigerate; for long-term storage freeze working aliquots and limit freeze-thaw cycles to preserve antibody activity.