Anti-SERINC2 Antibody

The SERINC2 (Serine Incorporator 2) target is a multi-pass transmembrane protein that facilitates serine incorporation into membrane phospholipids during lipid biosynthesis and has been characterized as a host restriction factor that impairs the infectivity of HIV-1 and other retroviruses. Antibodies.com offers this affinity-purified, unconjugated rabbit polyclonal antibody supplied in a 100 µl vial, validated for Western blot (WB) and immunohistochemistry (IHC) on human and mouse samples.

For Western blot, the reagent detects endogenous SERINC2 in whole-cell lysates and tissue homogenates, supporting expression studies at the protein level. In immunohistochemistry, it enables subcellular localization in formalin-fixed, paraffin-embedded sections, helping researchers map tissue distribution in normal and pathological specimens. To preserve antibody integrity, aliquot on receipt and store refrigerated, avoiding repeated freeze-thaw cycles. The polyclonal format provides recognition of multiple epitopes on SERINC2, which can improve signal across varied sample preparations and antibody dilutions.