Anti-Septin 8 Antibody

Septin 8 (SEPT8) is a GTP-binding protein of the conserved septin family, contributing to cytokinesis, actin and microtubule organization, and membrane compartmentalization in eukaryotic cells. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against SEPT8 and validated for Western blot and ELISA workflows. Confirmed reactivity spans human, mouse, and rat samples, supporting comparative cell biology and neuroscience studies where SEPT8 is enriched in neuronal tissue. The antibody is supplied as a 100 µl liquid aliquot and should be aliquoted and stored refrigerated to preserve activity across multiple freeze-thaw cycles. Researchers apply this reagent to investigate mitotic regulation, cytoskeletal remodeling, and reported interactions between SEPT8 and components linked to neurodegenerative disease research, including parkin-mediated ubiquitination pathways.