Anti-SEPT6 Antibody

Sourced through Antibodies.com, this affinity-purified reagent is a rabbit polyclonal antibody raised against an internal peptide sequence of human SEPT6 (septin 6), a GTP-binding cytoskeletal protein implicated in cytokinesis and membrane dynamics. The product is supplied at 50 µl per vial as a 1.0 mg/mL stock in phosphate-buffered saline (pH 7.4, 150 mM NaCl) supplemented with 0.02% sodium azide and 50% glycerol, with the unconjugated IgG formulated to minimise background in standard detection workflows. Endogenous levels of total SEPT6 are detected by the antibody, which the manufacturer recommends for Western blotting at a working dilution of 1:500–1:3000 and for immunohistochemistry at 1:50–1:100, and reactivity has been validated on human samples only. The reagent is shipped at 4 °C for cold-chain stability and should be aliquoted upon arrival and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve performance. For research-use applications that interrogate septin family biology — including studies of SEPT6 and its documented synonyms KIAA0128, SEP2, Septin-6 and SEPTIN6 — this polyclonal offers a flexible option for laboratories needing a clean, unconjugated primary antibody compatible with chromogenic, fluorescent or chemiluminescent detection systems. Each lot is affinity-purified from rabbit antiserum by epitope-specific affinity chromatography, helping ensure batch-to-batch consistency for WB and IHC assays run across multiple sample sets.