Anti-SEPSECS Antibody

This polyclonal reagent targets SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) synthase), the enzyme responsible for the final step in selenocysteine biosynthesis in human cells. Raised in rabbit and supplied as an unconjugated IgG preparation at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is provided as a 100 µl stock vial suitable for multiple experiments. Validated applications include Western blot, immunohistochemistry, and immunofluorescence on human tissue and cell samples, supporting studies of selenoprotein synthesis pathways and SEPSECS-related neurodegenerative conditions such as pontocerebellar hypoplasia type 2D. Researchers commonly pair this primary reagent with HRP- or fluorophore-conjugated secondary antibodies for downstream detection in immunoblotting and imaging workflows. Aliquot on first use to limit freeze-thaw cycles and store refrigerated in the supplied glycerol buffer to preserve antibody activity over the shelf life of the product. Distributed by Antibodies.com for research use only, this Primary Antibody is intended for laboratory investigation of human SEPSECS expression and subcellular localization.