Anti-SENP8 Antibody

Manufactured by Antibodies.com, this affinity-purified reagent is a rabbit polyclonal antibody raised against a synthetic peptide derived from the internal region of human SENP8 (also known as NEDP1, DEN1, Deneddylase-1, NEDD8-specific protease 1, or PRSC2). The unconjugated antibody is supplied at a concentration of 1.0 mg/mL in a 50 µL aliquot, formulated in phosphate buffered saline (without Mg²⁺ and Ca²⁺) at pH 7.4, containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol as a cryoprotectant. It is validated for Western Blotting (WB) and Immunohistochemistry (IHC) applications and has been confirmed to react with human, mouse, and rat samples, where it detects endogenous levels of the total SENP8 protein. The host species is rabbit, the clonality is polyclonal (Rabbit IgG), and the antibody is unconjugated, making it suitable for downstream detection with a secondary reagent of the researcher's choice. Storage and handling instructions are straightforward: the product is shipped at 4 °C, and upon receipt it should be aliquoted and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve activity. Intended solely for research use, this Antibodies.com polyclonal provides a reliable tool for laboratories investigating SUMO/sentrin and NEDD8 deconjugation pathways, in which SENP8 plays a key regulatory role.