Anti-SENP6 Antibody

Raised in rabbit against the SUMO-2/3-preferring deconjugating enzyme SENP6, this polyclonal antibody from Antibodies.com is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 15 mM sodium azide at approximately pH 7.2, packaged as a 100 µl vial of unconjugated reagent.

SENP6 is a member of the SENP cysteine protease family that edits polymeric SUMO-2/3 chains and liberates SUMO from conjugated substrates. Published work connects SENP6 activity to ribosome biogenesis, the DNA damage response, and mitotic chromosome segregation, making it a useful marker for studies of nucleolar SUMO turnover and chromatin-associated modification cycles in research use only workflows.

Recommended for Western blot and reactive against human, mouse, and rat samples, the reagent supports comparative work across standard mammalian model systems. The polyclonal format expands epitope coverage when probing full-length SENP6 or SUMO-bound complexes, and the 15 mM sodium azide formulation helps limit microbial contamination during routine bench handling of the vial.