Anti-SEMA3A Antibody

SEMA3A (Semaphorin 3A) is a secreted guidance cue originally characterized for its role in axon pathfinding during neural development, where it signals through neuropilin and plexin A receptors to repel growing axons. Subsequent studies have extended its relevance to immune cell regulation, vascular patterning, and tumor biology, including altered expression reported in melanoma and several other tumor types. This unconjugated rabbit polyclonal IgG preparation from Antibodies.com is raised against SEMA3A and has been validated for Western blot on human and mouse samples, providing a useful reagent for researchers tracking endogenous protein levels in cell lysates and tissue extracts.

Each vial is supplied as 200 µl of liquid antibody. For best results, aliquot the antibody upon arrival and store at -20 °C in single-use portions to limit repeated freeze-thaw cycles. The preparation recognizes the native SEMA3A protein on both human and murine samples, supporting reproducible detection in standard immunoblotting workflows.