Anti-SEMA3A Antibody

This unconjugated rabbit polyclonal IgG antibody from Antibodies.com targets Semaphorin 3A (SEMA3A), a secreted guidance cue best known for directing axon outgrowth during neural development through neuropilin-1 and plexin-A receptor complexes. Beyond the nervous system, SEMA3A influences immune cell behavior, including dampening of T-cell activation, and shapes vascular patterning through its effects on endothelial cells. The reagent is supplied as 100 µl of liquid in a single vial, unconjugated, and is validated for Western blot detection of endogenous target in human and mouse samples. Investigators working on developmental neurobiology, tumor microenvironment signaling, or immune checkpoint biology use this reagent to probe SEMA3A expression across cell lines and tissue lysates. The polyclonal format offers recognition of multiple epitopes, which can be useful when working with samples that may contain splice variants or post-translationally modified protein. Aliquot upon receipt and store refrigerated, avoiding repeated freeze-thaw cycles to preserve antibody activity across multiple experiments.