Anti-SELE Antibody

E-selectin (CD62E), the selectin-family adhesion glycoprotein expressed on cytokine-activated vascular endothelium, is the target of this unconjugated rabbit polyclonal antibody from Antibodies.com. The reagent supports detection of the leukocyte rolling receptor on inflamed vessel walls and is validated for western blot and immunohistochemistry across human, mouse, and rat samples.

Supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, the 100 µl volume is intended for storage at -20 °C, avoiding repeated freeze-thaw cycles. E-selectin serves as a marker of endothelial activation in cardiovascular, oncology, and inflammation research, including studies of atherosclerosis, sepsis, tumor angiogenesis, and ischemia-reperfusion injury.

The polyclonal clonality provides broader epitope coverage than a monoclonal reagent, increasing the chance of detecting the target even when a single epitope is altered or partially degraded in formalin-fixed tissue sections or denatured immunoblot membranes.