Anti-SEC24C Antibody

This polyclonal antibody from Antibodies.com targets SEC24C, a core component of the COPII inner coat complex that drives vesicle budding from the endoplasmic reticulum. SEC24C partners with SEC23 to form the inner coat lattice while recognizing transmembrane cargo destined for the Golgi apparatus, making the protein a key reference for researchers studying ER-to-Golgi anterograde transport and secretory pathway organization.

Raised in rabbit and supplied as an unconjugated IgG reagent in a 200 µl vial, the antibody is validated for Western blot on human samples, allowing detection of the endogenous SEC24C protein in lysates prepared from cultured cells or tissue. The unconjugated format gives flexibility to pair it with a secondary antibody of choice for chemiluminescent or fluorescent detection workflows.

Because SEC24C functions alongside paralogs SEC24A, SEC24B, and SEC24D, this reagent can be used to compare paralog expression patterns or to monitor changes in COPII coat composition under different cellular conditions, including pharmacological perturbation of the secretory pathway.