Anti-SDHB Antibody

This rabbit polyclonal antibody targets the iron-sulfur subunit B of succinate dehydrogenase (SDHB), a catalytic core component of mitochondrial respiratory Complex II embedded in the inner membrane. Manufactured by Antibodies.com, the unconjugated reagent is supplied as 100 µl of ready-to-use preparation and is validated for western blot and ELISA workflows. The antibody detects SDHB from human, mouse, and rat origin, supporting translational work in mitochondrial biology, metabolic disease research, and tumor biology where loss of SDHB expression is a recognized immunohistochemical marker for paraganglioma, pheochromocytoma, and gastrointestinal stromal tumors (GIST). Recommended uses include immunoblotting of whole-cell or mitochondrial lysates. Store refrigerated; protect from light and aliquot to minimize freeze-thaw cycles and preserve reagent activity across multiple experiments.