Anti-SDCBP Antibody

This rabbit polyclonal antibody from Antibodies.com targets SDCBP (Syndecan Binding Protein, also called Syntenin-1), a PDZ-domain adapter protein that couples transmembrane receptors to downstream effectors controlling intracellular trafficking, receptor clustering, and exosome biogenesis. It is supplied as 100 µl of unconjugated antiserum and has been validated for Western blot, immunohistochemistry, and immunofluorescence on human, mouse, and rat samples.

SDCBP organises signalling complexes at the inner leaflet of the plasma membrane and at endosomal compartments, recruiting partners that remodel the actin cytoskeleton, drive cell migration, and sort cargo into multivesicular bodies destined for secretion. The protein has been implicated in tumor cell invasion, metastatic dissemination, and the release of extracellular vesicles, which is why it appears frequently in oncology, neuroscience, and membrane-trafficking literature.

Because the reagent is unconjugated, researchers can pair it with HRP, biotin, Alexa Fluor, or DyLight secondaries according to the assay format. The polyclonal response recognises multiple epitopes on SDCBP, an advantage when probing truncated isoforms or post-translationally modified forms of the target. Aliquot on arrival and store at -20 degrees C to limit freeze-thaw loss across extended studies.