Anti-SDCBP Antibody

Syntenin-1 (SDCBP), a PDZ domain-containing cytosolic adapter that binds syndecans and couples them to downstream signaling, receptor trafficking, and exosome biogenesis, is the target recognized by this monoclonal reagent from Antibodies.com. Raised in mouse and purified in a 0.1 M Tris-Glycine buffer (pH 7.4) with 150 mM NaCl, 0.2% sodium azide, and 50% glycerol, the unconjugated IgG is supplied as 100 µl of working reagent for western blot workflows on human samples. Researchers studying melanoma progression, GPCR-mediated cell migration, or the assembly of multivesicular bodies use anti-SDCBP immunoblots to confirm expression levels and to follow shifts in syntenin-1 abundance after RNAi knockdown or CRISPR editing. The antibody is a primary reagent: no secondary conjugation is included, so laboratories pair it with their own HRP- or fluorophore-labeled anti-mouse secondaries depending on the detection platform. Storage at -20°C in the supplied glycerol buffer preserves activity through repeated freeze-thaw cycles for routine blotting use.