Anti-SDC2 Antibody

Raised in rabbit against syndecan-2 (SDC2), this polyclonal antibody from Antibodies.com targets a type I transmembrane heparan sulfate proteoglycan that anchors cells to the extracellular matrix and regulates growth factor signaling, cytoskeletal dynamics, and cell adhesion. Validated for Western blot and immunohistochemistry on human, mouse, and rat samples, it is supplied as a 100 µl aliquot at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, ready for direct use or further dilution in standard immunodetection workflows.

SDC2 is a cell-surface receptor that binds FGF-2, VEGF, and several extracellular matrix ligands, and it has documented roles in angiogenesis, wound repair, and tumor invasion. Its promoter methylation status has emerged as a clinically relevant biomarker, notably in non-invasive colorectal cancer screening, making well-characterised antibodies against the protein useful for both basic research and translational tissue studies. For routine handling, aliquot and store refrigerated; the glycerol-containing buffer protects the protein through multiple freeze-thaw cycles.