Anti-SCTR Antibody

The SCTR (Secretin Receptor) is a class B G protein-coupled receptor studied for its role in regulating pancreatic bicarbonate secretion, gastric emptying, and water homeostasis across epithelial tissues. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human SCTR target and is validated for two core research workflows: Western blot (WB) for protein-level expression analysis and immunohistochemistry (IHC) for localization studies in fixed tissue sections.

The antibody shows reactivity against both human and mouse samples, supporting cross-species expression profiling of secretin receptor distribution in pancreatic, biliary, gastrointestinal, and certain central nervous system tissues where the receptor has been documented. As a polyclonal reagent, it recognizes multiple epitopes on SCTR, which can improve signal recovery in applications where target abundance is limited or where partial protein degradation has occurred during sample preparation.

Supplied as 100 µl of unconjugated antisera, the format gives researchers flexibility to pair the primary reagent with their own secondary detection system, whether HRP, fluorophore, or biotin conjugates, across WB and IHC protocols.