Anti-SCNN1D Antibody

The polyclonal reagent targets SCNN1D, the delta subunit of the amiloride-sensitive Epithelial Sodium Channel (ENaC) family. Produced in rabbit as an IgG preparation, it is supplied as 50 µl of unconjugated antibody intended for Western blot workflows on human, mouse, and rat samples. SCNN1D is widely expressed in the central nervous system, pancreatic islets, kidney epithelium, and reproductive tissues, where it contributes to constitutive sodium flux across apical membranes. Researchers studying ion transport regulation, cystic fibrosis-related channel biology, and salt-sensitive hypertension models commonly probe this subunit alongside the better-characterized alpha, beta, and gamma ENaC counterparts. The polyclonal clonality allows recognition of multiple epitopes across the target protein, supporting standard immunoblot detection following SDS-PAGE separation. As a primary reagent, the antibody can be paired with HRP- or fluorophore-conjugated secondary antibodies for chemiluminescent or fluorescent readout. Small aliquots are recommended to preserve activity across repeated freeze-thaw cycles, with the unconjugated format offering flexibility to conjugate the antibody to user-preferred labels for research use only. This reagent is supplied by Antibodies.com.