Anti-SCNN1D Antibody

Antibodies.com offers this polyclonal reagent raised in rabbit against the SCNN1D target, delivered as an unconjugated IgG preparation in a 100 µl volume for western blot workflows. SCNN1D encodes the delta subunit of the epithelial sodium channel (ENaC), a membrane-bound complex that mediates passive sodium flux across polarized epithelia in tissues including kidney, lung, and the central nervous system, where it contributes to salt and water balance, mucociliary clearance, and neuronal membrane excitability.

The antibody recognizes the human SCNN1D protein and cross-reacts with mouse and rat orthologues, enabling comparative studies in rodent disease models and human tissue lysates. Because the reagent is unconjugated, it can be paired with a secondary antibody of the researcher's choice for chemiluminescent or fluorescent detection on nitrocellulose or PVDF membranes following standard SDS-PAGE transfer. Investigators examining ENaC subunit composition, acid-base regulation, or epithelial transport disorders use this reagent to probe expression patterns and abundance changes across experimental conditions.