Anti-SCN-pan Antibody

This polyclonal reagent from Antibodies.com targets the SCN-pan epitope conserved across voltage-gated sodium channel (NaV) family members, the transmembrane proteins responsible for action potential initiation and propagation in excitable cells. Raised in rabbit and supplied unconjugated at 1 mg/ml in phosphate buffered saline (pH ~7.3) with 0.05% sodium azide as preservative, the antibody is validated for Western blot on human, mouse, and rat samples. Researchers investigating neuronal excitability, cardiac electrophysiology, inherited channelopathies, and neuropathic pain mechanisms rely on pan-sodium channel antibodies to survey total channel expression across tissues and model systems. The 100 µl pack size supports multiple blotting experiments, and the polyclonal format increases the chance of detecting conserved epitopes even when individual isoform abundance is low. Refrigerate in the original vial upon receipt and aliquot to limit freeze-thaw cycles; the sodium azide helps inhibit microbial contamination during routine bench handling. This reagent complements isoform-selective tools, for example when comparing dorsal root ganglion versus hippocampal lysates, profiling cardiomyocyte cultures, or tracking developmental shifts in channel expression.