Anti-Scinderin Antibody

Scinderin is a calcium-dependent actin filament-severing protein of the gelsolin superfamily that regulates cytoskeletal dynamics and modulates regulated exocytosis in secretory cells. This polyclonal antibody, raised in rabbit and affinity-purified by Antibodies.com, recognizes human Scinderin and is supplied at 100 µl as an unconjugated reagent. The antibody has been validated for Western blot (WB) detection of Scinderin expression in cell lysates and for immunofluorescence (IF) localization of the protein in cultured cells and tissue sections. Researchers use it to probe Scinderin's role in platelet activation, chromaffin cell secretion, osteoclast bone resorption, and cytoskeletal remodeling in cancer cell migration. The polyclonal format delivers recognition of multiple epitopes on the Scinderin molecule, providing reliable signal across blotting and imaging workflows in laboratories studying vesicle release, actin remodeling, and signal-dependent cytoskeletal control.