Anti-SCG3 Antibody

This rabbit polyclonal IgG antibody targets SCG3 (Secretogranin III), a granin-family protein recognized for its role in the biogenesis and sorting of dense-core secretory granules within neuroendocrine cells. Beyond classical granule biology, SCG3 has been characterized in published studies as an antiangiogenic circulating factor and as a secreted adipokine relevant to metabolic research, with additional interest in its expression across neuroendocrine and tumor tissues. The unconjugated reagent is supplied at 50 µl per vial and is validated for western blot and immunohistochemistry workflows on human, mouse, and rat samples. It can be deployed to examine regulated secretory pathways, monitor SCG3 expression in tissue sections, or probe granule-mediated protein sorting in cell lysates. Produced in rabbit and affinity-purified, this Antibodies.com reagent offers an unconjugated format that pairs with standard secondary antibodies for chromogenic or fluorescent detection in research use only applications.