Anti-SCG2 Antibody

Secretogranin II (SCG2) is a member of the granin family found in the dense-core secretory granules of neuroendocrine cells, where it is processed into bioactive peptides including secretoneurin. This rabbit polyclonal antibody from Antibodies.com is raised against SCG2 and validated for Western blot (WB) and immunohistochemistry (IHC) on human tissue.

Researchers use this primary antibody to profile granin expression in endocrine cell populations and to characterize neuroendocrine tumors such as pheochromocytoma and small-cell lung carcinoma, where SCG2 complements chromogranin A as a tissue marker. Each vial is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, providing a 100 µl working stock suitable for freezer storage and repeated freeze-thaw cycles. The unconjugated format gives users freedom to pair the reagent with their preferred secondary reporter for chromogenic IHC, immunofluorescence, or chemiluminescent Western blot workflows without species cross-reactivity concerns from a pre-attached label.