Anti-SCAMP1 Antibody

Secretory Carrier Membrane Protein 1 (SCAMP1) is a key regulator of membrane trafficking and exocytosis in eukaryotic cells. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the SCAMP1 target and validated for Western blot detection across human, mouse, and rat samples, supporting comparative studies of vesicle recycling and secretion pathways in neuroscience and cell biology research.

The antibody is supplied as a 100 µl liquid aliquot at 1 mg/ml in phosphate buffered saline at approximately pH 7.2, with 0.05% sodium azide added as a preservative. For short-term use it can be kept refrigerated at 4°C; for longer storage, aliquot the solution and freeze at -20°C to preserve activity, and avoid repeated freeze-thaw cycles. Suggested working dilutions for Western blot generally range from 1:500 to 1:2000 depending on target expression levels and the detection chemistry employed.

SCAMP1 localizes primarily to the trans-Golgi network, plasma membrane, and recycling endosomes, where it modulates SNARE-mediated vesicle fusion. Researchers studying synaptic transmission, hormone secretion, or general membrane trafficking use this reagent to probe expression changes associated with neuronal signaling, cellular stress responses, and disease models involving secretory pathway dysfunction.