Anti-SCAF8 Antibody

This rabbit polyclonal antibody targets SCAF8 (SR-related CTD-associated factor 8), an RNA-binding protein also designated RBM16 that participates in pre-mRNA splicing regulation as part of the SR family of splicing regulators. The unconjugated IgG reagent is raised in rabbit and supplied by Antibodies.com at 100 µl per vial, intended for western blot detection of the human target.

SCAF8 contains characteristic arginine-serine rich domains that mediate protein-protein interactions within the spliceosome, and the antibody supports studies of RNA processing, transcription-coupled splicing events, and nuclear speckle organization. Reactivity is reported for human samples, and the polyclonal format provides multiple epitope recognition useful for researchers tracking endogenous SCAF8 expression across cell lines or characterizing its co-localization with other splicing factors.

Recommended applications include western blot analysis of whole-cell lysates and immunoblotting to confirm expression in human cell lines, along with downstream validation studies investigating the role of SCAF8 in alternative splicing regulation. For storage, aliquot the antibody and avoid repeated freeze-thaw cycles to preserve polyclonal IgG activity.