Anti-SBDS Antibody

This polyclonal antibody from Antibodies.com targets the SBDS (Shwachman-Bodian-Diamond Syndrome) protein, a factor required for ribosome biogenesis and RNA processing that is implicated in the inherited bone marrow failure disorder Shwachman-Diamond syndrome. The reagent is raised in Rabbit and supplied as an unconjugated liquid at 1 mg/ml in PBS containing 0.1% Sodium Azide and 50% Glycerol as a cryoprotectant.

Intended for Western blot and immunohistochemistry workflows, the antibody detects endogenous SBDS in Human, Mouse, and Rat samples, supporting comparative studies across mammalian model organisms and patient-derived tissue material. The 100 µl volume is enough for multiple blotting membranes or a series of stained tissue sections, and the 50% glycerol formulation permits convenient storage at -20 °C with minimal freeze-thaw handling between uses.

Laboratories investigating ribosome assembly, neutrophil maturation, pancreatic exocrine function, or the molecular basis of bone marrow failure can deploy this reagent to confirm expression patterns, validate knockout or knockdown cell models, and complement functional assays. Because it is polyclonal, the antibody recognizes multiple epitopes of SBDS, which can strengthen signal in immunoprecipitation and immunofluorescence setups beyond the validated Western blot and immunohistochemistry applications.