Anti-SALL4 Antibody

For developmental biology and oncology laboratories, this polyclonal rabbit IgG from Antibodies.com is validated for the SALL4 transcription factor across western blot and immunofluorescence workflows.

SALL4 (Spalt-like transcription factor 4) is a C2H2 zinc-finger protein that controls pluripotency in embryonic stem cells, regulates limb and central nervous system patterning during early embryogenesis, and becomes re-expressed in germ cell tumors as well as several solid carcinomas, which is why it serves as a diagnostic marker in tumor pathology.

The unconjugated antibody cross-reacts with both human and mouse SALL4 protein, supporting comparative studies between model organisms and clinical specimens. Each vial ships with 50 µl of liquid formulation ready for immunoblotting of whole-cell lysates or indirect fluorescence staining of cultured cells and tissue sections.

Researchers apply this reagent to investigations of pluripotency factor networks, germ cell tumor classification, hepatocellular carcinoma progression, and developmental patterning. Cold-chain storage is recommended between uses, and the product should be handled according to standard IgG antibody protocols for research use only.