Anti-SALL4 Antibody

The Anti-SALL4 reagent from Antibodies.com is a rabbit polyclonal IgG antibody raised against the SALL4 transcription factor, supplied as 200 µl of unconjugated antiserum. It is validated for western blot and immunofluorescence workflows and shows reactivity with both human and mouse samples, supporting comparative studies in stem cell biology, developmental research, and cancer biology.

SALL4 is a zinc-finger transcription factor that maintains pluripotency in embryonic stem cells and is re-expressed in several solid and hematologic malignancies, including hepatocellular carcinoma, germ cell tumors, and acute myeloid leukemia. Researchers use this polyclonal antibody to probe SALL4 expression in cell lysates by western blot and to visualize subcellular localization by immunofluorescence staining. The polyclonal format offers broader epitope coverage than a monoclonal reagent, which is helpful when detecting truncated or post-translationally modified SALL4 isoforms.

Typical workflows include lysing cultured cells or tissue homogenates for western blot analysis, or fixing and permeabilizing samples for immunofluorescence imaging. The unconjugated format allows end users to couple the antibody to their preferred fluorophore or HRP label, which is convenient for laboratories running multiple detection chemistries. Short-term storage at 4 °C is recommended, and aliquoting is advised to limit freeze-thaw cycles and preserve antibody titer over time. For research use only.