Anti-SALL4 Antibody

From Antibodies.com, this rabbit polyclonal IgG reagent targets the SALL4 zinc finger transcription factor, a nuclear protein of the Spalt family that governs pluripotency in embryonic stem cells and early embryonic patterning. Aberrant re-expression of SALL4 has been reported in acute myeloid leukemia, hepatocellular carcinoma, germ cell tumors, and breast cancer, keeping the protein at the center of cancer stem cell biology and tumor marker research.

The antibody is supplied as 100 µl of unconjugated serum in a single vial and is validated for Western blot and immunofluorescence workflows on human and mouse samples. Its polyclonal format enables recognition of multiple epitopes on native SALL4, supporting studies of transcriptional regulation, lineage specification, and tumor pathology where the expected nuclear staining pattern aids interpretation. Researchers commonly apply it to characterize pluripotent stem cell populations and to profile germ cell tumor biopsies expressing SALL4.

For routine use, refrigerate working aliquots and protect from light to limit freeze-thaw damage and preserve binding activity across repeated experiments. Centrifuge briefly before each pull to recover contents from the vial cap.